A Pilot Comparison of 2D and 1D MR Spectroscopic Quantitation of Metabolites in Healthy Human Brain at 3T
نویسندگان
چکیده
Introduction: Due to the added second dimension, 2D MR spectroscopy (MRS) offers better spectral dispersion of metabolite resonances minimizing the overlap in the spectral domain, which may improve the overall quantitation accuracy [1]. 2D JPRESS can be easily implemented by modifying the conventional PRESS sequence by encoding the J evolution around the last 180 rf pulse [2]. Localized 2D shift correlated spectroscopy (L-COSY) was proposed as a way to further improve the spectral dispersion along the second spectral dimension [1,3]. The goal of this pilot project was to compare the specificity of metabolite quantitation offered by ProFit [4] processed 2D JPRESS and L-COSY data with 1D PRESS processed by LC-Model.
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